Aminobenzoic acids and derivatives
![Chemscene 5-[[2-(Trifluoromethyl)phenyl]methyl]-1 3 4-thiadiazol-2-amine | 250mg | CS-W012724 | 98% | 1052694-84-4 | MFCD11137510 | 259 26 | C10H8F3N3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Chemscene 5-[[2-(Trifluoromethyl)phenyl]methyl]-1 3 4-thiadiazol-2-amine | 250mg | CS-W012724 | 98% | 1052694-84-4 | MFCD11137510 | 259 26 | C10H8F3N3S
Chemscene | 5-[[2-(Trifluoromethyl)phenyl]methyl]-1 3 4-thiadiazol-2-amine | 250mg | CS-W012724 | 98% | 1052694-84-4 | MFCD11137510 | 259 26 | C10H8F3N3S
Chemscene (S)-( )-1-Cbz-3-Pyrrolidinol | 25g | CS-W014735 | 97% | 100858-32-0 | MFCD07784363 | 221 26 | C12H15NO3
Chemscene | (S)-( )-1-Cbz-3-Pyrrolidinol | 25g | CS-W014735 | 97% | 100858-32-0 | MFCD07784363 | 221 26 | C12H15NO3
Chemscene Methyl 1H-pyrrole-2-carboxylate | 10g | CS-W013518 | 98% | 1193-62-0 | MFCD00817048 | 125 13 | C6H7NO2
Chemscene | Methyl 1H-pyrrole-2-carboxylate | 10g | CS-W013518 | 98% | 1193-62-0 | MFCD00817048 | 125 13 | C6H7NO2
Chemscene 4 -Chloro-3 -(trifluoromethyl)acetophenone | 25g | CS-W013110 | 98% | 129825-11-2 | MFCD03094146 | 222 59 | C9H6ClF3O
Chemscene | 4 -Chloro-3 -(trifluoromethyl)acetophenone | 25g | CS-W013110 | 98% | 129825-11-2 | MFCD03094146 | 222 59 | C9H6ClF3O
Chemscene 3-Chloro-4-(trifluoromethoxy)benzonitrile | 25g | CS-W013129 | 98% | 129604-26-8 | MFCD01631557 | 221 56 | C8H3ClF3NO
Chemscene | 3-Chloro-4-(trifluoromethoxy)benzonitrile | 25g | CS-W013129 | 98% | 129604-26-8 | MFCD01631557 | 221 56 | C8H3ClF3NO
Medchemexpress LLC Ac-IETD-CHO | 191338-86-0 | MFCD01318858 | 98.6% | 502.52 | C21H34N4O10 | 5 MG
Ac-IETD-CHO is a tetrapeptide aldehyde (Ac-Ile-Glu-Thr-Asp-CHO) that reversibly inhibits granzyme B and caspase-8; it is used in research to block caspase-8-dependent apoptosis and related cellular processes.
- Purity 98.6% (HPLC).
- Molecular weight 502.52 Da.
- Chemical formula C21H34N4O10.
- Sequence Ac-Ile-Glu-Thr-Asp-CHO.
- Soluble in DMSO up to 100 mg/mL; in vivo formulations reported at ≥2.5 mg/mL.
- Storage powder -80°C (2 years) or -20°C (1 year); keep sealed and dry.
- Available pack size 5 mg.
AdipoGen Chrysomycin A
Chemical. CAS 82196-88-1. Formula C28H28O9. MW 508.5. Isolated from Streptomyces sp. Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines.
Chemscene p-Anisic acid | 100g | CS-B1766 | 98% | 100-09-4 | MFCD00002542 | 152 15 | C8H8O3
Chemscene | p-Anisic acid | 100g | CS-B1766 | 98% | 100-09-4 | MFCD00002542 | 152 15 | C8H8O3
Chemscene 5-Chloro-4-chloro-1H-pyrrolo[2 3-b]pyridine | 5g | CS-D0119 | 98% | 1142192-58-2 | MFCD12401653 | 187 029 | C7H4Cl2N2
Chemscene | 5-Chloro-4-chloro-1H-pyrrolo[2 3-b]pyridine | 5g | CS-D0119 | 98% | 1142192-58-2 | MFCD12401653 | 187 029 | C7H4Cl2N2
Apexbio Technology LLC Obatoclax mesylate (GX15-070) 803712-79-0 25mg
Obatoclax mesylate (GX15-070) is a small-molecule inhibitor targeting multiple anti-apoptotic proteins within the BCL-2 family including BCL-2 BCL-XL MCL-1 A1 and BCL-B It functions by binding to their BH3-binding grooves thereby disrupting interactions with pro-apoptotic proteins such as Bak and Bim promoting apoptotic processes Obatoclax mesylate induces apoptosis in cultured acute myeloid leukemia (AML) cells and primary AML patient samples evidencing inhibitory effects on clonogenic growth with IC50 values below 200 nmol/L In preclinical research applications this compound shows activity in xenograft models of solid tumors and multiple myeloma providing a relevant chemical tool for oncology research focused on apoptotic mechanisms and hematologic malignancies
AdipoGen Cyclosporin A
Chemical. CAS 59865-13-3. Formula C62H111N11O12. MW 1202.6. Isolated from Tolypocladium inflatum. Potent immunosuppressant same as FK-506 Prod. No. AG-CN2-0047 and rapamycin Prod. No. AG-CN2-0025. Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B PP2B calcineurin. Prevents the dephosphorylation of nuclear factor of activated T cells NFAT transcription factor, leading to disruption of T cell activation. Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 IL-2. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases e.g. atopic dermatitis and with potential anti-rheumatic activity rheumatoid arthritis. Antibacterial. Antifungal. Antiparasitic. Apoptosis inhibitor.